Table 1.

Clinico-pathological characteristics and treatment of adult patients suffering from PDLG with malignant astrocytic cells including our case

Age	Gender	Survival	First Symptoms	Localization	Biopsy	Autopsy	Radiotherapy	Chemotherapy	Reference
43	M	< 1	headache, nausea, facial nerve paresis	Cr, SC	-	+	-	-	[15]
51	M	2	IRP, back pain	Cr, SC	+	-	-	+ CYC, ADR, 5FU, MTX it	[10]
47	M	2	headaches, altered consciousness, numbness in both arms	Cr	+	-	-	+ MTX it	[16]
23	F	< 3	IRP, seizures	Cr	-	+	-	-	[12]
52	M	3	low back pain, numbness of both legs	Cr, SC	+	+	+ (craniospinal)	+ MCNU, Interferon	[17]
63	F	3	IRP, headache, coma	Cr, BrS	+	+	-	+ CYC	[11]
19	M	3	IRP	Cr, SC	-	+	-	-	[18]
25	M	5	IRP	Cr, BrS, SC	+	+	-	-	[19]
71	M	7	back stiffness	SC	-	+	-	-	[2]
50	M	7	IRP, polyneuritis cranialis	Cr, BrS, SC	+	+	-	-	[5]
19	M	11	holocephalic headache, nausea, vomitus, left-sided weakness	Cr, SC	+	-	+ (craniospinal)	+ TMZ	[13]
60	M	12	blurred vision, back pain	SC	+	-	+ (spinal)	-	[20]
24	M	13	holocephalic headache, neck pain, diplopia, confusion	Cr, SC	+	-	-	+ 12c × TMZ/BCNU	[13]
40	F	17	ataxia, incontinence, obstipation	Cr	+	-	-	+ 7c × TMZ, AUC + ETO, BCNU	[14]
53	M	24	seizures, gait disturbance, paraparesis, sensory disturbance	Cr, SC	+	-	+ (craniospinal)	+11c xTMZ, INN, DDP, INT, BVZ	our case

5-FU = 5-fluouracil, ADR = Adriamycin, AUC 5 = Carboplatine, BCNU = Carmustine, BrS = brainstem, BVZ = Bevacizumab, c = cycle, CA = Cytarabine, CCNU = Lomustine, Cr = Cranial, CYC = Cyclophosphamide, DDP = Cisplatin, ETO = Etoposide, INN = topotecan, INT = Irinotecan, IRP = raised intracranial pressure, it = intrathecally, MCNU = Ramustine, MTX = Methotrexate, SC = spinal cord, TMZ = Temozolomide, TOP = Thiotepa, Vincristine, Prednison