Table 1.
Sample description | Negative | Positive | % Positive | Total | P value (χ2 test) | ||
---|---|---|---|---|---|---|---|
HERV-K mRNA expression assessed by RT-PCR | |||||||
Breast cancer tissue | 12 | 28 | 70.0 | 40 | |||
Uninvolved breast tissue | 32 | 8 | 20.0 | 40 | |||
Normal breast tissue |
40 |
0 |
0.0 |
40 |
<0.0001a |
||
Sample description |
– |
+ |
++ |
+++ |
% Positive |
Total |
P value (χ2 test) |
HERV-K protein expression assessed by IHC | |||||||
Benign tissues | 18 | 12 | 0 | 0 | 40.0 | 30 | |
Cancer tissues | 15 | 11 | 25 | 59 | 86.4 | 110 | <0.0001b |
Comparison of the positive expression rate of the 3 groups using contingency table analysis χ2 (and Fisher’s exact) test by GraphPad Prism 5.
Comparison of the positive expression rate of the 2 groups using contingency table analysis χ2 (and Fisher’s exact) test by GraphPad Prism 5.