Table 2.
Association between HERV-K env Expression Levels and Clinicopathological Characteristics in Chinese Breast Cancer Patients
| Clinical parameter | Total | +/++ (%) | +++ (%) | P value (χ2 test) |
|---|---|---|---|---|
| Age | 95 | 0.866 | ||
| ≤60 | 73 | 28 (38.4) | 45 (61.6) | |
| >60 | 22 | 8 (36.4) | 14 (63.6) | |
| Tumor size | 95 | 0.002 | ||
| ≤3cm | 60 | 30 (50.0) | 30 (50.0) | |
| >3 cm | 35 | 6 (17.1) | 29 (82.9) | |
| Histologic grade | 0.086 | |||
| I or II | 72 | 31 (43.1) | 41 (56.9) | |
| III | 23 | 5 (21.7) | 18 (78.3) | |
| Clinical stage | 0.010 | |||
| I | 8 | 6 (75.0) | 2 (25.0) | |
| II | 57 | 24 (42.1) | 33 (57.9) | |
| III | 30 | 6 (20.0) | 24 (80.0) | |
| Number of lymph node metastases | 0.023 | |||
| 0 | 39 | 19 (48.7) | 20 (51.3) | |
| 1-3 | 21 | 10 (47.6) | 11 (52.4) | |
| ≥4 | 35 | 7 (20.0) | 28 (80.0) | |
| ER | 0.257 | |||
| <15% | 44 | 14 (31.8) | 30 (68.2) | |
| ≥15% | 51 | 22 (43.1) | 29 (56.7) | |
| PR | 0.796 | |||
| <15% | 57 | 21 (36.8) | 36 (63.2) | |
| ≥15% | 38 | 15 (39.5) | 23 (60.5) | |
| Recurrence and metastasis | 0.241 | |||
| No | 73 | 30 (41.1) | 43 (58.9) | |
| Yes | 22 | 6 (27.3) | 16 (72.7) | |
| Death | 0.049 | |||
| No | 81 | 34 (42.0) | 47 (58.0) | |
| Yes | 14 | 2 (14.3) | 12 (85.7) |
Note: Comparison of the 2 groups using contingency table analysis χ2 (and Fisher’s exact) test by GraphPad Prism 5. ER = estrogen receptor; PR = progesterone receptor.