Table 4.
Association of HERV-K Positivity with Disease Stage
| Stage | % HERV-K positive d(n +/N total) | % Tumor with <50% tumor cell positivitya (n) | % Tumor with >50% tumor cell positivityb (n) |
|---|---|---|---|
| DCIS | 53 (9/17) | 33 (3) | 67 (6) |
| I | 52 (17/33) | 35 (6) | 65 (11) |
| II | 62 (64/103) | 15 (10) | 85 (54) |
| III/IV | 62 (26/42) | 11 (3) | 89 (23) |
| cTotal | 59 (116/195) | 19 (22) | 81 (94) |
DCIS = ductal carcinoma in situ.
a
Less than 50% of tumor cells stained positive for HERV-K.
b
Greater than 50% of tumor cells stained positive for HERV-K.
c
Total = DCIS + I + II+ II/IV.
d
N +/N total = number of positive samples/ number of total cases.