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Effects of FDH expression on DNA damage and intracellular ATP pool. (A) DNA damage was evaluated in FDH-expressing HCT116 cells (36 hours posttransfection) and A549 cells (48 hours postinduction). Etoposide (5 µM for 4 hours) was used as a positive control. (B) ATP levels were measured in A549 (24 hours postinduction) and HCT116 (24 hours posttransfection). Error bars represent ± SD (n = 3).
