Table 4.
Effect of rutin (RT) and/or ascorbic acid (AA) on plasma level of creatinine in high-cholesterol diet (HCD) fed rats following 6 weeks of supplementation
| Treatment (in rat chow) |
Creatinine (μmol/l) | |
|---|---|---|
| Male | Female | |
| Control | 51.94 ± 12.59 | 35.59 ± 9.71 |
| RT (0.2%) | 49.76 ± 6.94 | 32.91 ± 14.13 |
| AA (0.4%) | 51.21 ± 4.52 | 35.21 ± 12.03 |
| RT (0.1%) + AA (0.2%) | 55.21 ± 2.98 | 44.77 ± 14.21 |
| HCD (1% cholesterol + 0.5% cholic acid) | 43.95 ± 6.53 | 36.35 ± 13.88 |
| RT (0.2%) + HCD | 54.12 ± 9.29 | 47.07 ± 16.54 |
| AA (0.4%) + HCD | 55.93 ± 20.93 | 42.10 ± 11.40 |
| RT (0.1%) + AA (0.2%) + HCD | 53.39 ± 12.84 | 37.12 ± 9.79 |
Data were expressed as Mean ± S.D and analyzed using one-way ANOVA followed by Student Newman-Keuls method as post hoc test. Six rats were used in each group