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Relationship of IPT1 to membrane-localized lipid rafts in C. albicans biofilms. (a–c) Distribution of lipid rafts in biofilms formed by isogenic (a) wild-type, (b) Δipt1 mutant, and (c) Δipt1/IPT1 revertant. Rafts were visualized by staining with the fluorescent dye filipin. (d–f) SEM analyses of biofilms formed by (d) wild-type, (e) Δipt1 mutant, and (f) Δipt1/IPT1 revertant (scale bars in SEM images, 10 µm).
