Table 4.
Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio and Kappa values for each syncope criteria for mortality
| OESIL (95% CI) |
SFSR (95% CI) |
EGSYS (95% CI) |
ASR > 1 (95% CI) |
ASR > 2 (95% CI) |
|
|---|---|---|---|---|---|
| Sensitivity | 0.90 (0.54 to 0.99) |
1 (0.66 to 1.00) |
0.80 (0.44 to 0.97) |
1 (0.66 to 1) |
1 (0.66 to 1) |
| Specificity | 0.76 (0.70 to 0.82) |
0.70 (0.63 to 0.76) |
0.80 (0.74 to 0.85) |
0.63 (0.56 to 0.69) |
0.78 (0.72 to 0.83) |
|
True positive (PPV) |
0.15 (0.07 to 0.27) |
0.13 (0.07 to 0.23) |
0.15 (0.07 to 0.29) |
0.11 (0.06 to 0.20) |
0.17 (0.09 to 0.30) |
| False positive | 0.85 (0.74 to 0.93) |
0.87 (0.77 to 0.93) |
0.85 (0.71 to 0.93) |
0.89 (0.80 to 0.94) |
0.83 (0.70 to 0.91) |
|
True negative (NPV) |
0.99 (0.96 to 1.00) |
1 (0.97 to 1.00) |
0.99 (0.96 to 1.00) |
1 (0.97 to 1) |
1 (0.97 to 1) |
| False negative | 0.006 (0.00 to 0.04) |
0 (0.00 to 0.03) |
0.01 (0.00 to 0.04) |
0 (0 to 0.03) |
0 (0 to 0.03) |
| Positive LR | 3.83 (2.79 to 5.24) |
3.30 (2.70 to 4.03) |
4.02 (2.67 to 6.04) |
2.70 (2.27 to 3.20) |
4.60 (3.58 to 5.91) |
| Negative LR | 0.13 (0.02 to 0.84) |
0 (0 to 0) |
0.25 (0.07 to 0.86) |
0 (0 to 0) |
0 (0 to 0) |
|
Kappa for mortality |
0.31 | 0.30 | 0.29 | 0.26 | 0.37 |
ASR: Anatolian Syncope Rule; CI: confidence interval; EGSYS: Evaluation of Guidelines in Syncope Study; LR: likelihood ratio; NPV: negative predictive value; OESIL: Osservatorio Epidemiologico sulla Sincope nel Lazio; PPV: positive predictive value; SFSR: San Francisco Syncope Rule.