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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Neural Transm (Vienna). 2011 Jul 12;119(1):59–71. doi: 10.1007/s00702-011-0684-8

Fig 1. Integrin αvβ3 staining in post-mortem human brain tissue.

Fig 1

Endothelial cells of human post-mortem brain tissue were labeled with mouse anti-human integrin αvβ3 antibody and visualized with the chromagen DAB. Integrin αvβ3 reactive vessels are shown in post-mortem tissues from non-pathological controls, incidental Lewy Body Disease (iLBD), Parkinson’s disease (PD) and progressive supranuclear palsy (PSP) subjects. Note the distinct pattern of staining along vessels. In most cases only a small portion of the longitudinal vessel is stained. In other cases the vessels are perpendicular resulting in a ring of staining. The grey cells seen in the SNpc are neuromelanin-containing cells that are evident in unstained tissues and could be distinguished from the αvβ3 staining by stain color (in the original color images), and by morphology. Black scale bars = 100 μm.