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. 2012 Jan;158(Pt 1):107–118. doi: 10.1099/mic.0.052035-0

Fig. 1.

Fig. 1.

Amino acid sequences of transmembrane domain 6 (TM-VI) of S. cerevisiae Ste2 and Ste3, C. neoformans Cpr2 and T. atroviride Gpr1. Substitution of the conserved proline for leucine in Ste2 and Ste3 results in constitutive activation (*) of the respective receptors (Baldwin, 1993). The leucine resulting in constitutive activity of Cpr2, Ste2 and Ste3 is in bold.