Figure 4.

Competitive release of resistant parasites following the removal of sensitive competitors by chemotherapy. The total number of resistant parasites present in infections where sensitive parasites have been removed by drug treatment or allowed to remain (no drugs) are shown. Plotted points are the mean (±SEM) cumulative total number of Plasmodium chabaudi parasites present in peripheral blood of mice, based on three to five infections per group. Therapeutic treatment is applied when the hosts first start to show symptoms of malaria (weight loss, anemia); prophylactic treatment is applied at the time host are infected. Data from Wargo et al. (2007), and de Roode et al. (2004) respectively.