Table 8.
Observed FDR for the Infinium HumanMethylation27 array when using the raw p-value (Raw), Benjamini & Hochberg (BH), Benjamini & Yekutieli (BY), Holm step down (Holm), the default q-value method which estimates π0 using a smoothing method (q-smoother), and the q-value method where π0 is estimated using the bootstrap (q-bootstrap).
Dataset | Raw | BH | BY | Holm | q-smoother | q-bootstrap |
---|---|---|---|---|---|---|
Rakyan CD14+ | 0.698 | 0.036 | 0.012 | 0.006 | 0.045 | 0.045 |
Rakyan CD4 | 0.452 | 0.033 | 0.011 | 0.004 | 0.033 | 0.033 |
Bell Yoruba 1 | 0.646 | 0.052 | 0.018 | 0.011 | 0.060 | 0.063 |
Bell Yoruba 2 | 0.446 | 0.028 | 0.013 | 0.009 | 0.036 | 0.035 |
Liu | 0.563 | 0.030 | 0.010 | 0.013 | 0.030 | 0.030 |