Table 5.
Comparison by level of care (academic vs. non-academic clinic) in primary target values and parameter settings (absolute numbers and percent (%) in parenthesis)
| Academic Hospital | Non-Academic Hospital | Differences between institutions | |
|---|---|---|---|
| N = 48 | N = 142 | p-value | |
| Oxygen therapy | |||
| FiO2 | |||
| 0.21 | 15/45 (33) | 41/138 (30) | |
| 0.22 - 0.5 | 26/45 (58) | 79/138 (57) | 0.728 |
| 0.51 - 1.0 | 4/45 (9) | 18/138 (13) | |
| Target SpO2 | |||
| < 85% | 12/47 (26) | 18/129 (14) | |
| 85-90% | 34/47 (72) | 92/129 (71) | 0.023 |
| > 90% | 1/47 (2) | 19/129 (15) | |
| High FiO2, taper down | 7/48 (15) | 31/140 (22) | |
| Low FiO2, taper up | 41/48 (85) | 109/110 (78) | 0.260 |
| Non-invasive respiratory support | |||
| Prolonged inflations > 5 sec | 11/46 (24) | 36/138 (26) | 0.770 |
| Starting CPAP | |||
| ≤ 3 cmH20 | 3/45 (7) | 7/135 (5) | |
| 4-5 cmH20 | 31/45 (69) | 108/135 (80) | 0.288 |
| > 5 cmH20 | 11/45 (24) | 20/135 (15) | |
| Invasive respiratory support | |||
| INSURE yes | 12/47 (26) | 39/123 (32) | 0.432 |
| Surfactant | |||
| 100 mg/kg | 30/39 (77) | 113/127 (89) | 0.109 |
| 150-200 mg/kg | 9/39 (13) | 14/127 (11) | |
CPAP = continuous positive airway pressure
FiO2 = fraction of inspired oxygen
SpO2 = peripheral saturation of oxygen
INSURE = intubate, surfactant application, extubate immediately