. 2011 Nov 1;3(1):53–57. doi: 10.1021/ml200217u

Table 2. HINT Scores by Fragment and Interaction Type.

		HINT score^a
		ring	ester
compd	mode	H_TOTAL	H_HB + H_AB	H_HH	H_AA + H_BB	H_HP
1	I	492	858	711	–499	–1328
7a	I	518	680	583	–427	–1048
7b	I	363	1069	855	–593	–1681
7c	I	321	766	833	–478	–1821
7d	II	570	778	226	–398	–1169
7e	II	626	781	225	–364	–1015
7f	II	435	665	387	–369	–1046
7g	II	589	812	284	–341	–868
7h	II	557	549	268	–336	–1071
7i	II	581	726	237	–400	–1027
7j	II	650	375	213	–236	–634
7k	II	596	847	196	–403	–755
7l	II	587	827	494	–240	–924

Interaction types: favorable polar (hydrogen bond, H_HB, and acid/base, H_AB), hydrophobic (H_HH), unfavorable polar (acid/acid, H_AA, and base/base, H_AB), and unfavorable hydrophobic polar (H_HP).