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Normalized biodistribution of 14C-labeled paclitaxel loaded into nanomicelles in nude mice with SKOV-3 xenografts (organs/muscle).
The ratio of liver/muscle decreased dramatically within 16 hours post injection, even though it showed the highest ratio in the beginning. The ratio of skin/muscle increased up to around 5-fold. The ratio of tumor/muscle kept increasing to a peak of around 8.5-fold and showed much higher levels than those of organs/muscle after 16 hours.
