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. 2012 May 15;7(5):e35237. doi: 10.1371/journal.pone.0035237

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Rogers et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Top: Location of the congenic regions for the congenic strains used is plotted, along with boundary-defining markers for SJL congenics (brown). Blue indicates 129 congenics, with dark blue indicating those congenics that demonstrate a statistically significant difference in angiogenic response. Genes are indicated next by which DNA strand they are coded by. Finally regions of shared haplotype are indicated colored by whether the parental strains have disparate (black) or shared (grey) alleles at AngFq5. Below: Magnification of the region of interest defined by the R82 and R06 congenics. The number of genes, and genes bearing amino-acid altering polymorphisms (cSNPs), is indicated as are the locations of the pink-eyed dilution gene (p) and the tyrosinase gene (c). Scale is in Mbp on build 37.1 of mouse Chromosome 7.