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. 2012 May 15;7(5):e36815. doi: 10.1371/journal.pone.0036815

Figure 1. Gene expression in alveolar macrophages and in peripheral blood.

Figure 1

A. mRNA levels of ET-1, TNFα, IL-1β, MCP-1, MIP-1α and IL-18 in alveolar macrophages in HF patients (n = 20) and controls (CTR, n = 16). B. Gene expression of the same mediators in peripheral blood cells. Gene expression was assessed by real-time quantitative RT-PCR in relation to the control gene18S rRNA. C. mRNA levels of ET-1, TNFα, IL-6 and MCP-1 in alveolar macrophages from HF patients (n = 20) and controls (CTR, n = 16) where mRNA levels in HF patients are separated into tertiles (T) according to left ventricular ejection fraction (LVEF) (T1, LVEF 34–47%; T2, 27–34%; T3, 20–25%). Gene expression was assessed by real-time quantitative RT-PCR in relation to the control gene18S rRNA. Data are mean±SEM. *p<0.05 and **p<0.01 versus controls.