Figure 5. Western blot was performed to detect Leptin receptors in adipogenic and osteogenic MSCs.

Two variants of Leptin receptors were present at ∼100 kD and ∼125 kD. The normal control sample (Ctrl) was from a 20-year-old girl and the AIS sample (AIS) was from a 15-year-old girl (Cobb angel = 68°). The level of leptin receptor was obviously lower in AIS sample.