Figure 6. The effect of leptin on adipogenesis of MSCs from a normal control (18y, male) and an AIS patient (15y, male, Cobb angle = 54°).

Cells from the normal control were induced along the adipogenic differentiation with human recombined leptin protein at concentration of 0 µg/mL (a), 0.015 µg/mL (b) and 0.6 µg/mL (c). MSCs from the AIS patient were also treated under the same condition that containing leptin of 0 µg/mL (d), 0.015 µg/mL (e) and 0.6 µg/mL (f). At day 12, the cells were subjected to Oil Red O staining. Scale bar = 500 µm.