Table 3. Results of the Case-control association studies.
SNPs | Genotypea | P-value | OR (95%CI)c | ||
Case(n = 446) | Control(n = 550) | Allele | Genotypeb | ||
L1 | 441/5/0 | 545/5/0 | 0.739 | 0.922 | 1.234(0.356–4.278) |
L2 | 127/228/91 | 166/291/93 | 0.246 | 0.885 | 1.111(0.930–1.327) |
L3 | 444/2/0 | 548/2/0 | 0.834 | 0.999 | 0.811(0.114–5.766) |
L4 | 298/148/0 | 396/148/6 | 0.209 | 0.965 | 1.169(0.916–1.491) |
L5 | 354/88/4 | 452/96/2 | 0.213 | 0.648 | 1.206(0.898–1.620) |
L6 | 225/188/33 | 290/222/38 | 0.492 | 0.944 | 1.071(0.880–1.305) |
The three values in the “genotype” column indicate the numbers of homozygotes(major allele)/heterozygotes/homozygotes(minor allele) in each SNP, respectively.
After adjusting for age, gender and BMI by logistic regression.
Calculated for the alleles.
Bonferroni adjustment (All SNPs P adjusted = 1).