Skip to main content
. Author manuscript; available in PMC: 2013 May 15.
Published in final edited form as: Biochemistry. 2012 May 1;51(19):4035–4048. doi: 10.1021/bi300378n

Figure 1.

Figure 1

Electron density maps for complexes of ADH with NAD+ and the fluoroalcohols. Interactions in the proton relay system shown in dashed lines. The dotted line with label 3.4 Å shows the distance between C4N of the nicotinamide ring and the methylene carbon of the alcohol. The stereoviews are rotated about 180° in order to see different views. (A) Binding of pentafluorobenzyl alcohol. Electron density is at about 4 σ above the mean. (B) Binding of trifluoroethanol. Electron density is at about 4.9 σ above the mean.