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. Author manuscript; available in PMC: 2013 May 15.
Published in final edited form as: Biochemistry. 2012 May 1;51(19):4035–4048. doi: 10.1021/bi300378n

Figure 2.

Figure 2

Interactions of alcohols with active site residues. The coordination of the catalytic zinc ion and the hydrogen bonds of the alcohol in the proton relay system are shown as dotted lines. The riding hydrogens of the methylene carbons are shown in cyan and the other atoms have usual atomic coloring, except that the alternative conformations of the side chains of Leu-57 and Leu-309B (other subunit) are shown in green. Note that the conformations of Leu-57 and Leu-116 differ in the two structures. (A) Pentafluorobenzyl alcohol. (B) Trifluoroethanol.