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A. K562 were engineered to express PSGL-1 (K562/PSGL-1). B. K562 and K562/PSGL-1 have low endogenous levels of fucosylation and become heavily fucosylated following treatment with FT-VI. C. Only FT-VI-treated (fucosylated) K562/PSGL-1 cells showed improved homing to femoral marrow.