Figure 3. Effector functions of CD8 T cells required for graft rejection are not measurably impaired by the absence of γδ T cells.
(A) Graft survival for K5mOVA (n=8) and TCRδ-/-OVA+/- (n=8) grafts, transplanted respectively onto C57 and TCRδ-/- mice immunized with OVA + QuilA (P= N.S) (B) Graft survival for K5mOVA or TCRδ-/-OVA+/- (n=8) grafts, transplanted separately onto 2C TCR Tg Rag-/- mice transferred with 1×103 in vitro activated OT-I cells (P=N.S). (Graft survival curves were assessed for significance using Kaplan-Meier survival analysis).