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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Biol Psychiatry. 2012 Jan 29;72(1):25–33. doi: 10.1016/j.biopsych.2011.12.012

Figure 4. Injecting NaB Into the Dorsal Hippocampus Increases CA1 Histone Acetylation.

Figure 4

A) NaB (n = 6,7) injected into the dorsal hippocampus enhanced acetylation (A) and c-Fos (B) in the dorsal hippocampus relative to vehicle (n=6,7) regardless of whether extinction was strong (3 min) or weak (24 min). C) Individual injector placements are shown in the left panel. Representative immunohistochemistry demonstrating that dorsal hippocampal infusions of NaB increases H3 Lys14 acetylation and c-Fos in the dorsal hippocampus are shown in the inset right panel. As no difference was observed between Extinction Duration or interaction between Extinction Duration and Drug Treatment, only representative images from NaB and Veh injections are shown. Stereotaxic image reproduced with permission from [26].