Table 3.

The association between three MRI measures and memory performance in a regression model simultaneously including all 3 measures^a

MRI measure	All participants R2 = 0.51		High R2 = 0.56		Low R2 = 0.52
	Estimateb (SE)	p-value	Estimate (SE)	p-value	Estimate(SE)	p-value
GM (%TCV)	9.42 (3.67)	0.01	0.14 (8.64)	0.99	−0.19 (8.39)	0.98
WMHc	−0.20 (0.06)	0.002	−0.33(0.08)	< 0.001	−0.11 (0.10)	0.32
MPF_LIPd	1.32 (0.40)	0.002	0.45 (0.53)	0.40	2.11 (0.63)	0.002

Abbreviations: Whole = whole group of participants; High = high gray matter group (above median gray matter volume); Low = low gray matter group(below median gray matter volume); GM = gray matter; WMH = white matter hyperintensity; TCV = total brain volume; MPF_LIP = connectivity between medial prefrontal and left inferior parietal regions.

^aEpisodic memory: composite measure of Word list learning I and Word list learning II; Gender, education and adjusted age (residual age against GM and WMH) were controlled in the regression model.

^bUnstandardizied coefficients from regression models carried out on original (unstandardized) variables.

^cResiduals of log transformed WMH percentage of total brain volume on GM.

^dAbsolute values of fisher Z transformed correlation coefficients