Table 1.
Demographics and baseline characteristics of subjects
| 1 mg daily (n = 234) | 30 mg monthly (n = 229) | 50 mg monthly (n = 229) | |
|---|---|---|---|
| Sex, n (%) | |||
| Male | 2 (0.9) | 7 (3.1) | 5 (2.2) |
| Female | 232 (99.1) | 222 (96.9) | 224 (97.8) |
| Age (years) | 67.8 [6.870] | 68.6 [7.19] | 67.3 [6.53] |
| Body mass index (kg/m2) | 21.88 [3.101] | 21.87 [2.875] | 22.03 [3.248] |
| Menopause (years) | 50.0 [4.20] | 49.9 [3.81] | 49.5 [4.57] |
| Existing vertebral fractures, n (%) | 60 (25.6) | 61 (26.6) | 72 (31.4) |
| Lumbar BMD (g/cm2) | 0.6474 [0.06406] | 0.6527 [0.06023] | 0.6481 [0.06493] |
| Lumbar BMD (T-score) | −3.0551 [0.53830] | −3.0112 [0.50616] | −3.0494 [0.54561] |
| Total hip BMD (g/cm2) | 0.6684 [0.07949] | 0.6644 [0.08213] | 0.6685 [0.08765] |
| Total hip BMD (T-score) | −2.8791 [0.66802] | −2.9129 [0.69021] | −2.8784 [0.73656] |
| Serum 25(OH)D (ng/mL) | 27.0 [5.76] | 26.9 [5.94] | 25.8 [5.53] |
| Serum BALP (U/L) | 27.98 [9.165] | 27.07 [8.687] | 29.32 [14.321] |
| Serum osteocalcin (BGP, ng/mL) | 8.71 [2.756] | 8.61 [2.543] | 8.60 [2.205] |
| Serum intact PTH (pg/mL) | 42.2 [13.20] | 43.7 [14.45] | 44.1 [14.72] |
| Serum Ca (mg/dL) | 9.31 [0.343] | 9.29 [0.321] | 9.33 [0.335] |
| Urine DPD (nmol/mmol) | 6.47 [2.072] | 6.54 [2.145] | 6.38 [2.175] |
| Urine NTX (nmol BCE/mmol Cr) | 46.85 [21.527] | 45.67 [19.720] | 46.49 [20.692] |
Data are means [SD] for the indicated number of subjects in each group