Table 2.
Antidopaminergic drug use. Time before index date | Antiemetic/anxiolytic antidopaminergic drugs* |
Other antidopaminergic drugs† |
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Crude‡, OR (95% CI) | Model 1§, OR (95% CI) | Model 2¶, OR (95% CI) | Crude‡, OR (95% CI) | Model 1§, OR (95% CI) | Model 2¶, OR (95% CI) | |
No use | 1 | 1 | 1 | 1 | 1 | 1 |
Current (0–114 days) | 1.9 (1.4 to 2.6) | 1.4 (1.0 to 1.9) | 0.9 (0.6 to 1.2) | 1.4 (1.1 to 1.6) | 1.1 (0.9 to 1.4) | 0.8 (0.6 to 0.9) |
Recent (115–180 days) | 3.1 (1.6 to 5.7) | 2.5 (1.3 to 4.9) | 1.6 (0.8 to 3.0) | 1.8 (0.9 to 3.4) | 1.4 (0.7 to 2.8) | 1.2 (0.6 to 2.4) |
Past (6–12 months) | 2.3 (1.4 to 3.9) | 1.8 (1.0 to 3.0) | 1.1 (0.6 to 1.9) | 2.3 (1.5 to 3.7) | 1.9 (1.2 to 3.1) | 1.5 (0.9 to 2.4) |
Former (>12 months) | 3.2 (2.3 to 4.5) | 2.1 (1.5 to 3.0) | 1.5 (1.0 to 2.1) | 1.5 (0.9 to 2.4) | 1.1 (0.7 to 1.8) | 1.0 (0.6 to 1.6) |
No use of antidopaminergic drugs is the reference category.
Dixyrazine, levomepromazine, melperone and prochlorperazine.
Fluphenazine, perphenazine, flupenthixole, thioridazine, chlorpromazine, haloperidol, pimozide, ziprasidone, aripiprazole, quetiapine, risperidone, paliperidone, clozapine and olanzapine.
Adjusted for age and sex.
Adjusted for history of alcohol-related comorbidity.
Adjusted for history of alcohol-related diagnoses or drugs for alcoholism, chronic obstructive lung disease, ischaemic heart disease, obesity, diabetes, opioid use, gallstone disease, educational level, marital status and number of concomitant medications.