Table 4.
Efficacy results based on tick and flea count reduction as compared to the baseline counts on Day 0
| Results | Cat study | Dog study | ||||||
|---|---|---|---|---|---|---|---|---|
| Efficacy ** | Fleas | Ticks | Fleas | Ticks | ||||
| Treatment group | IVP | CP | IVP | CP | IVP | CP | IVP | CP |
| SD2-4 (96 h) curative | 92.9* | 71.8 | 94.8 | 97.7 | 86.7* | 66.5 | 79.9 | 86.6 |
| month 1 | 99.0* | 87.1 | 94.0 | 96.3 | 94.1 | 48.6 | 93.4* | 85.2 |
| month 2 | 99.7* | 57.1 | 99.3* | 90.7 | 98.0* | 28.2 | 97.8* | 81.4 |
| month 3 | 100* | 90.2 | 97.9* | 90.0 | 97.4* | 48.6 | 98.8* | 81.1 |
| month 4 | 99.8* | 76.9 | 100* | 96.6 | 99.1* | 56.1 | 98.2* | 86.9 |
| month 5 | 97.4* | 68.1 | 99.4 | 100 | 97.5* | 51.0 | 98.8* | 83.4 |
| month 6 | 99.1* | 63.9 | 99.6 | 96.3 | 99.6* | 60.5 | 98.5 | 88.0 |
| month 7 | 99.8* | 87.4 | 100 | 100 | 99.9* | 67.3 | 97.9 | 88.0 |
| month 8 | 99.3* | 87.8 | 99.6 | 100 | 100 | 69.8 | 91.2* | 79.9 |
| m 8 (+14 d) (SD238) | 99.8* | 96.1 | 100 | 100 | 100* | 67.8 | 99.8 | 90.7 |
| Overall | 98.3* | 79.3 | 98.4* | 96.9 | 96.7* | 57.9 | 94.7* | 85.6 |
*Efficacy of IVP is statistically superior to CP (p < 0.05; ANOVA adjusted for baseline or non-parametric Wilcoxon test), as evaluated from PP population**Efficacy calculations (PP population) were based on arithmetic means