Figure 2.

Interpreting results of non-inferiority trials [11]. Footnotes for Figure 2. *This CI indicates noninferiority in the sense that it does not include Δ, but the new treatment is significantly worse than the standard. Such a result is unlikely because it would require a very large sample size. †This CI is inconclusive in that it is still plausible that the true treatment difference is less than Δ, but the new treatment is significantly worse than the standard.