. Author manuscript; available in PMC: 2012 May 16.

Published in final edited form as: J Alzheimers Dis. 2011;25(4):707–717. doi: 10.3233/JAD-2011-102133

Table 2.

Co-existing, non-Alzheimer’s neuropathological features.

Parameter	Preclinical Alzheimer’s disease (pAD) (n = 32)	Normal (n = 89)	p
Brain Weight (mean g ± SD)	1190.8±119.9	1244.3±124.7	0.039^†
Brain Weight^* (mean g ± SE)	1205.9±11.5	1254.7±11.5	0.033
LBD (% cases)	3.1	3.4	0.947^‡
Macro infarct (% cases)	31.3	30.3	0.923^‡
Lacunar infarct (% cases)	6.3	3.4	0.483^‡
Microinfarct (% cases)	59.4	41.6	0.083^‡
Hemorrhagic infarct (% cases)	12.5	2.5	0.022^‡
Amyloid angiopathy (% cases)	84.4	46.7	<0.0001^‡
Atherosclerosis (% cases)	96.7	78.6	0.022^‡

adjusted for age and gender;

^†

t-test

^‡

Chi-square test