Table 3.
Release rates of CX from polymeric preparations.
| Polymer | Release rates assessed at 22°C (min−1) | Release rates assessed at 37°C (min−1) | ||||||
|---|---|---|---|---|---|---|---|---|
| 1st stage | SD | 2nd stage | SD | 1st stage | SD | 2nd stage | SD | |
| pNIPAM-A-CX | 2.85 × 10−3 | 0.01 × 10−3 | 1.74 × 10−3 | 0.02 × 10−3 | 4.98 × 10−3 | 0.02 × 10−3 | 2.80 × 10−3 | 0.26 × 10−3 |
| pNIPAM-B-CX | 2.62 × 10−3 | 0.02 × 10−3 | 2.15 × 10−3 | 0.05 × 10−3 | 4.79 × 10−3 | 0.04 × 10−3 | 2.50 × 10−3 | 0.18 × 10−3 |
| pNIPAM-C-CX | 7.43 × 10−3 | 0.04 × 10−3 | 7.57 × 10−4 | 0.40 × 10−4 | 5.37 × 10−3 | 0.04 × 10−3 | 5.26 × 10−3 | 0.39 × 10−3 |
| MC-CX | 1.66 × 10−3 | 0.03 × 10−3 | — | — | 1.22 × 10−2 | 0.01 × 10−2 | — | — |
| PA-CX | 3.60 × 10−5 | 0.04 × 10−5 | — | — | 4.09 × 10−5 | 0.05 × 10−5 | — | — |
| H2O-CX | 3.29 × 10−3 | 0.07 × 10−3 | — | — | 1.06 × 10−2 | 0.03 × 10−2 | — | — |
pNIPAM-A-CX, pNIPAM-B-CX, pNIPAM-C-CX: preparations of respective polymers detailed in the text with chlorhexidine, MC-CX: preparation of methylcellulose and chlorhexidine, PA-CX: preparation of polyacrylic acid and chlorhexidine, and H2O-CX: aqueous dispersion of chlorhexidine, data from repeated six experiments.