Table II.
Regions of significant activation from Model 1: Task‐related activity and interactions with age and disease
Region | X | Y | Z | t | |
---|---|---|---|---|---|
Aging (positive correlation) | |||||
Cingulate | L | −10 | −18 | 52 | 6.04 |
R | 8 | −12 | 52 | 4.81 | |
Primary Motor Cortex | R | 40 | −24 | 52 | 5.03 |
PreMotor Cortex | R | 26 | −30 | 68 | 3.86 |
R | 22 | −28 | 68 | 3.73 | |
Primary Motor Cortex | L | −40 | −18 | 54 | 4.07 |
L | −44 | −20 | 54 | 4.0 | |
L | −36 | −20 | 52 | 3.97 | |
L | −30 | −30 | 50 | 3.97 | |
Somatosensory Cortex | R | 62 | −14 | 40 | 4.43 |
R | 20 | −46 | 68 | 3.52 | |
Precuneus/Somatosensory | L | −14 | −48 | 70 | 3.49 |
Inferior Frontal Gyrus | L | −30 | −34 | 12 | 4.28 |
Aging (negative correlation) | |||||
Anterior Cingulate | R | 10 | 36 | 12 | 5.18 |
PD vs. Controls | |||||
PreMotor Cortex | L | −36 | −6 | 62 | 5.32 |
L | −20 | −12 | 72 | 3.94 | |
L | −44 | −6 | 56 | 3.82 | |
SMA | L | −8 | −14 | 48 | 4 |
L | −2 | 0 | 58 | 3.78 | |
R | 2 | 0 | 54 | 3.74 | |
Middle Temporal | L | −58 | −38 | 12 | 5.03 |
R | 66 | −46 | −2 | 3.6 | |
Superior Temporal Gyrus | L | −64 | −14 | 14 | 4.35 |
Cerebellum | R | 26 | −52 | −22 | 4.36 |
R, right; L, left; XYZ, coordinates of maximal activated voxel in standard anatomic space using the MNI template; t, Maximum t level at this voxel. P < 0.05 FDR.