Table 1.
Patient characteristics and Popeye domain containing 3 expression in gastric cancer n (%)
| Clinical parameters |
Popdc3 |
||||
| n | Low | High | χ2 | Pvalue | |
| Age (yr) | |||||
| < 50 | 105 | 72 (68.6) | 33 (31.4) | ||
| ≥ 50 | 201 | 156 (77.6) | 45 (22.4) | 2.968 | 0.085 |
| Gender | |||||
| Male | 199 | 148 (74.4) | 51 (25.6) | ||
| Female | 107 | 80 (74.8) | 27 (25.2) | 0.006 | 0.940 |
| Size (cm) | |||||
| < 5 | 154 | 120 (77.9) | 34 (22.1) | ||
| ≥ 5 | 152 | 108 (71.1) | 44 (28.9) | 1.901 | 0.168 |
| Histology | |||||
| Papillary adenocarcinoma | 8 | 5 (62.5) | 3 (37.5) | ||
| Tubular adenocarcinoma | 209 | 151 (72.2) | 58 (27.8) | ||
| Mucinous adenocarcinoma | 52 | 42 (80.8) | 10 (19.2) | ||
| Signet ring cell carcinoma | 37 | 30 (81.1) | 7 (18.9) | 3.084 | 0.379 |
| Histologic differentiation | |||||
| Well | 17 | 13 (76.5) | 4 (23.5) | ||
| Moderate | 100 | 67 (67) | 33 (33) | ||
| Poor | 177 | 140 (79.1) | 37 (20.9) | ||
| Undifferentiated | 12 | 8 (66.7) | 4 (33.3) | 4.439 | 0.109 |
| Invasion depth | |||||
| T1 | 24 | 10 (41.7) | 14 (58.3) | ||
| T2 | 63 | 32 (50.8) | 31 (49.2) | ||
| T3 | 181 | 149 (82.3) | 32 (17.7) | ||
| T4a | 28 | 24 (85.7) | 4 (14.3) | ||
| T4b | 10 | 7 (70.0) | 3 (30.0) | 48.566 | < 0.0001 |
| Regional lymph nodes | |||||
| N0 | 163 | 94 (57.7) | 69 (42.3) | ||
| N1 | 41 | 39 (95.1) | 2 (4.9) | ||
| N2 | 54 | 49 (90.7) | 5 (9.3) | ||
| N3a | 20 | 14 (70.0) | 6 (30.0) | ||
| N3b | 27 | 19 (70.4) | 8 (29.6) | 52.504 | < 0.0001 |
| Distant metastasis | |||||
| M0 | 274 | 197 (71.9) | 77 (28.1) | ||
| M1 | 32 | 31 (96.9) | 1 (3.1) | 9.412 | 0.002 |
| TNM stages | |||||
| I | 73 | 30 (41.1) | 43 (58.9) | ||
| II | 109 | 81 (74.3) | 28 (25.7) | ||
| III | 92 | 86 (93.5) | 6 (6.5) | ||
| IV | 32 | 31 (96.9) | 1 (3.1) | 70.624 | < 0.0001 |
TNM: Tumor, nodes, metastasis; Popdc3: Popeye domain containing 3.