Table 2.

Multivariate analysis for disease-related deaths (Cox regression model)

Variables	Pvalue	Hazard ratio	95% CI
Popdc3	< 0.0001	0.193	0.133-0.282
Gender	0.016	1.388	1.063-1.814
Regional lymph nodes	< 0.0001	1.344	1.156-1.564
Distant metastasis	< 0.0001	11.591	6.131-21.915
TNM stages	0.002	1.486	1.159-1.905

CI: Confidence interval; TNM: Tumor, nodes, metastasis; Popdc3: Popeye domain containing 3.