Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2012 May 16.

Published in final edited form as: Clin Pharmacol Ther. 2010 Dec 22;89(2):210–216. doi: 10.1038/clpt.2010.255

Table 5.

Frequency of tolerant/intolerant by dose group.

			SLCO1B1 genotype score
		All	0	1	2	3	4	P(trend)
Low dose (<40mg)	Intolerant (%)	178 (24.2)	13 (22.8)	51 (23.8)	79(26.0)	33(21.9)	2(18.2)
Low dose (<40mg)	Tolerant	559 (75.9)	44 (77.2)	163 (76.2)	225 (74.0)	118 (78.2)	9 (81.8)	0.8076

High dose (≥40mg)	Intolerant	638 (47.1)	35 (38.5)	186(44.4)	242(47.1)	153(51.9)	22 (62.9)
High dose (≥40mg)	Tolerant	716 (52.9)	56 (61.5)	233 (55.6)	272(52.9)	142 (48.1)	13 (37.1)	0.0023