Figure 7.

ACE inhibitor and ARB treatment does not affect expression of full length amyloid precursor protein (APP) in the aged 3xTGAD mouse. Full length APP was assessed by western blot in the soluble protein fraction extracted from fresh-frozen brain tissue. Samples from each treatment group were randomly loaded onto one of 3 gels run concurrently, with a single control sample loaded onto all three gels as a reference sample. The relative intensity of each band was normalised to the mean of the 3 reference sample intensities. Data were analysed by 1-way ANOVA with significance set at P<0.05.