Table 3.
Expression of Oxidative Stress Genes in the Terminal Ileum of Neonatal Rats Raised in Room Air (RA) and hyperoxia/hypoxia (H/H). Data are folded expression difference from Maternally-Fed RA or H/H.
| Genes of Interest | Un-supplemented Formula | Prebiotics | Probiotics | Synbiotics | ||||
|---|---|---|---|---|---|---|---|---|
| RA | H/H | RA | H/H | RA | H/H | RA | H/H | |
| CAT | -2096 | -1.5 | -634 | -1.2 | -634 | -3.9 | -2051 | -2.0 |
| GPX1 | -3 | -1.4 | -1 | 1.2 | 1 | 2.0 | -2 | -1.8 |
| GPX2 | -22 | 11.5 | -2 | 8.4 | -6 | 24.5 | -8 | 10.5 |
| GPX3 | -28 | -1.5 | 1 | -2.6 | 9 | 1.4 | 12 | -9.0 |
| GPX4 | -29 | 2.3 | -4 | 1.6 | 3 | -1.5 | -7 | 1.2 |
| GPX5 | -1546 | -2.4 | -355 | -2.4 | -455 | -26.0 | -542 | -10.7 |
| GPX6 | -645 | -1.2 | -140 | -1.4 | -191 | -14.6 | -162 | 3.7 |
| GPX7 | -2288 | -2.1 | -80 | -1.2 | -120 | -1.6 | -174 | -2.8 |
| SOD-1 | -15 | 1.2 | 12 | 1.1 | 11 | 1.1 | 15 | 1.4 |
| SOD-2 | -28 | 1.5 | -13 | 1.9 | -18 | 2.5 | -17 | 1.8 |
| SOD-3 | -101 | -3.0 | -7 | -1.3 | -29 | -1.4 | -19 | -4.7 |
Genes of interest are: Cat, catalase; GPX, glutathione peroxidase; SOD, superoxide dismutase