Figure 1.
(A) Effect of neonatal acetic acid treatment on sensitivity to colorectal distention (CRD) in 8-week-old rats. AWR (abdominal withdrawal reflex) scores (y-axis) as a function of distention pressure, (x-axis). AA = acetic acid treated; saline = saline treated; n = 6 each (P < 0.001; Welch 2-sample t-test). (B) Effect of neonatal acetic acid treatment on stool water content, pellet number and bodyweight. These results are normalized to the average values in control (P10 saline) group (*P < 0.05).