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. Author manuscript; available in PMC: 2012 Sep 16.
Published in final edited form as: Cell. 2012 Mar 16;148(6):1188–1203. doi: 10.1016/j.cell.2012.02.022

Figure 5. Rainbow amyloid.

Figure 5

Novel amyloid dyes can be used as surrogate probes of the supramolecular structure of protein aggregates. Shown are Aβ plaques (yellow) and Aβ amyloid angiopathy (green) in an AβPP transgenic mouse (carrying the AβPP Swedish and AβPP Dutch mutation). Note the different spectral signatures upon staining with the luminescent conjugated polythiophene tPTAA (bottom left). The image was recorded using a combination of green and red filters. Scale bar = 20um.