Weights were monitored in two phases: during morphine administration (indicated by the grey shading), and during the recovery period. For the first 7 days, we found that morphine treatment led to weight loss independent of surgery condition (A and B). During the recovery period, the effect of morphine treatment on weight in the sham-operated rats waned across days (A). Contused rats treated with highest dose of morphine, however, gained significantly less weight than both sham-operated and saline-treated controls.