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. Author manuscript; available in PMC: 2013 Apr 11.
Published in final edited form as: J Am Chem Soc. 2012 Mar 29;134(14):6218–6223. doi: 10.1021/ja2106477

Figure 5.

Figure 5

Cellular incorporation of LOs is deterred by cell-surface sialic acid and GAGs. (A) LO 4 (10 μM, n = 3) was incubated with CHO cells deficient in sialic acid (Lec-2) and wild-type cells (Pro-5). (B) LO 3 (10 μM, n = 3) was incubated with CHO cells deficient in heparan sulfate and chondroitin sulfate (CHO-745) and wild-type cells (CHO-K1). Error bars: ±SD. Student’s t-test gave two-tailed p-values of 0.0001 and 0.0371 for panels A and B, respectively.