Chemical structures of different phytochemical polyphenol antioxidants (A–G). Phytochemical polyphenols have their structural origin from the simple phenolic (benzene) ring and having two or more hydroxyl (OH) groups offer their polyphenolic nature and name of their class of compounds. These are compounds that are bioactive natural products and act as free-radical quenchers, potent antioxidants, trace metal-complexing molecules, pro-oxidants, and regulators of cell proliferation. More strikingly, they are emerging as the modulators of epigenetic regulation of gene expression.