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. 2012 Mar 20;9(1):3. doi: 10.1186/1559-0275-9-3

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Copyright ©2012 Angel et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Heat map showing the changing protein abundances in the CSF as a function of reduction of A) neopterin and B) NFL levels in the CSF. Average protein abundances measured in CSF samples (grouped by neopterin and NFL values indicated in the heatmap labels) are shown in A and B. Network analysis of proteins with significant cross correlation with neopterin and NFL resulted in the identification of two distinct networks of proteins with related disease and functional associations shown in C and D.