Table 1.
Subject and CSF background characteristics
| HIV Infected Baseline | HIV Infected All Samples Median (IQR)* | HIV Negative | |
|---|---|---|---|
| Number | 14 | 79 | 12 |
| Age (mean years, SD) | 46.6 (7.6) | 48.0 (7.9) | 45.7 (5.1) |
| Gender (M/F) | 12/2 | 59/20 | 10/2 |
| Blood T cells (mean cells/μL, SD) | |||
| CD4+ | 217.1 (155.9) | 268.2 (166.7) | 902.4 (265.4) |
| CD8+ | 896.1 (573.0) | 933.7 (662.7) | 481.9 (243.6) |
| HIV-1 RNA (log10 copies/mL) | |||
| plasma | 4.29 (3.74 - 5.15) | 3.40 (1.72 - 4.76) | NA |
| CSF | 4.92 (4.26 - 5.36) | 3.85 (1.71 - 4.47) | NA |
| CSF WBCs (per μL) | 15 (6.3 - 20.3) | 11 (5.0 - 22.0) | 1.0 (0.3 - 2.0) |
| CSF Neopterin (nMol/L) | 34.8 (22.2 - 48.7) | 23.6 (14.0 - 44.3) | 4.6 (3.3 - 6.2) |
| CSF NFL (ng/L) | 124 (124 - 1846) | 235.2 (124.0 - 2460.0) | 124 (124 - 124) |
| QNPZ-4 | -1.30 (-3.43 - 0.28) | -1.70 (-3.35 - 0.45) | 0.00 (-0.85 - 0.46) |
| CSF:blood albumin ratio (mean, SD) | 7.946 (3.508) | 7.818 (4.074) | 5.355 (2.055) |
* Unless otherwise designated as mean and SD