Table 1. An accelerated stability study of SFT in the gel formulation.
Intervals | % Inhibition of HIV-1 infectiona | |||||||
SFT in gel | SFT in PBS | |||||||
4°C | RTb | 30°C | 40°C | 4°C | RT | 30°C | 40°C | |
Week 0 | 91.34±0.84 | 89.71±2.03 | 91.63±0.38 | 94.16±1.89 | 89.09±1.97 | 88.21±2.71 | 89.15±2.76 | 88.84±2.11 |
Week 1 | 80.54±1.04 | 96.84±1.15 | 92.09±1.70 | 94.91±2.88 | 94.69±1.64 | 92.08±1.23 | 92.62±2.31 | 94.48±1.41 |
Week 2 | 87.05±0.87 | 93.95±3.45 | 94.26±2.63 | 88.23±3.27 | 85.21±0.94 | 89.56±3.86 | 92.20±2.57 | 86.36±0.98 |
Week 3 | 89.76±0.16 | 87.28±1.88 | 89.51±0.49 | 88.77±2.35 | 88.71±3.41 | 84.64±1.47 | 90.68±0.11 | 81.73±4.66 |
Week 4 | 93.33±0.95 | 96.25±2.04 | 99.10±0.35 | 99.27±0.26 | 84.77±0.87 | 81.82±3.37 | 98.82±0.95 | 87.92±3.74 |
Week 5 | 93.80±1.63 | 95.03±1.69 | 93.92±1.10 | 87.92±2.72 | 92.61±2.88 | 93.79±2.43 | 90.54±0.68 | 92.67±1.24 |
Week 6 | 90.99±0.44 | 93.47±1.73 | 92.81±1.65 | 87.88±0.57 | 90.61±1.36 | 88.01±3.06 | 90.20±2.16 | 88.89±4.43 |
Week 7 | 93.22±4.43 | 90.64±1.70 | 89.66±4.01 | 92.32±1.02 | 93.16±1.44 | 92.06±1.01 | 93.67±0.82 | 92.80±1.80 |
Week 8 | 93.02±0.77 | 91.31±3.30 | 90.88±4.58 | 82.70±2.36 | 91.30±1.54 | 90.89±1.67 | 87.76±4.09 | 91.33±2.25 |
Data represent mean ± SD (n = 3).
RT: room temperature.