Table 2. Genetic interactions of mir-51 family with precocious developmental timing mutants.
Precocious Alaeb | ||||
Straina | complete | gapped | none | n |
RG733 wild type | 0 | 0 | 100 | 9 |
RF481 wild type | 0 | 0 | 100 | 12 |
RF491 mir-51 | 0 | 0 | 100 | 14 |
RF499 mir-52 | 0 | 0 | 100 | 13 |
RF483 mir-53 | 0 | 0 | 100 | 15 |
RF399 mir-54/55/56 | 0 | 0 | 100 | 13 |
RF692 mir- 52/53/54/55/56 | 0 | 0 | 100 | 15 |
RG490 mir-48(ve33) | 0 | 55 | 45 | 47 |
RF583 mir-52; mir-48(ve33) | 0 | 88d | 12 | 34 |
RF534 hbl-1 | 0 | 76 | 24 | 41 |
RF535 mir-52; hbl-1 | 2d | 95 | 2 | 44 |
RF563 lin-14ts @25°C | 34 | 66 | 0 | 29 |
RF588 mir-52; lin-14ts @25°C | 76d | 20 | 4 | 25 |
RF536 lin-41 | 0 | 11 | 89 | 38 |
RF537 mir-52; lin-41 | 0 | 14 | 86 | 36 |
RF538 lin-42 | 0 | 89 | 11 | 37 |
RF541 mir-52; lin-42 | 3 | 93 | 3 | 29 |
VT517 lin-28 c | 5 | 90 | 5 | 20 |
RF573 mir-52; lin-28 c | 0 | 100 | 0 | 20 |
full genotype information can be found in Table S1.
alae were scored in L3 molt or early L4-stage worms, except where otherwise noted.
alae were scored in the L2 molt.
indicates significant difference between strains of same genotype +/− mir-52 (χ2, p<0.05).