Figure 4. Resveratrol exerts dosage dependent anti- vs. pro-senescence effect on hMSCs.

A). Cells were stained in X-gal (blue color) and neutral red solution (red color). Images were taken at 200× magnification. B). Percentages of senescent cells vs. total cells were determined based on images taken. At least 184 total cells from each treatment condition were counted. Column represents the relative fold changes of percentage of cells undergoing senescence in each treatment group normalized to the value obtained in the BM treated cells. Data was obtained from three independent experiments. Error bars represent standard deviation. *: p≤0.01 vs. BM.