Table 2. Estimated interaction coefficients from ANOVA of the 23 selected ISGs and corresponding P values.
Gene Symbol | Estimate (%) | P value | Adjusted P value1 |
SAMD4A 2 | −45.5333 | 0 | 0 |
IRF2 | −44.0567 | 0 | 0 |
MDA5 | −36.7333 | 0 | 0 |
RIG-I | −36.2433 | 0 | 0 |
SSBP3 | −32.2667 | 0 | 0 |
C5orf39 | −29.8 | 0 | 0 |
PSMB9 | −24.1333 | 0 | 0 |
MYD88 | −23.7333 | 0 | 0 |
PHF11 | −18.6333 | 0 | 1.00E−04 |
IRF7 | −17.9667 | 0 | 2.00E−04 |
IFIT5 | −17.5667 | 0 | 2.00E−04 |
IFITM3 | −17.5333 | 0 | 2.00E−04 |
CXCL9 | −16.4 | 1.00E−04 | 7.00E−04 |
BTN3A3 | −11.8333 | 0.0031 | 0.023 |
UPP2 | −11.2 | 0.0051 | 0.0355 |
SMAD3 | −11.0333 | 0.0057 | 0.0374 |
MAB21L2 | −10.1667 | 0.0107 | 0.0534 |
COMMD3 | −9.4667 | 0.0172 | 0.0688 |
RASSF4 | −9 | 0.0233 | 0.0932 |
SAMHD1 | −5.9333 | 0.1318 | 0.2707 |
S100A8 | −5.2667 | 0.1804 | 0.3609 |
FLJ3973 | 1.6 | 0.7386 | 0.7386 |
IL28RA | 11.92 | 0.0029 | 0.023 |
The P values were adjusted using Hommel's adjustment for multiple comparisons.
Genes in bold font showed statistically significant synergy with ZAP (P<0.05).