Table 3. Summary of ISGs that showed significant synergy with ZAP in the top-23 screen and the larger confirmatory screens.
| Gene Symbol | Top 23 Screen | Larger Screen #1 | Larger Screen #2 | Larger Screen #3 | Pooled Larger Screens |
| BATF2 | NT1 | ✓2 | |||
| BTN3A3 | ✓ | ||||
| C10orf10 | NT | ✓ | |||
| C4orf33 | NT | ✓ | |||
| C5orf39 | ✓ | ✓ | ✓ | ✓ | ✓ |
| CCDC109B | NT | ✓ | ✓ | ||
| CCDC75 | NT | ✓ | |||
| CTCFL | NT | ✓ | |||
| CXCL9 | ✓ | ||||
| DDIT4 | NT | ✓ | |||
| DEFB1 | NT | ✓ | |||
| FAM70A | NT | ✓ | |||
| GBP5 | NT | ✓ | |||
| GCH1 | NT | ✓ | |||
| IFI44L | NT | ✓ | |||
| IFIT5 | ✓ | ||||
| IFITM3 | ✓ | ||||
| IL28RA | ✓ | ✓ | ✓ | ||
| IRF1 | NT | ✓ | ✓ | ✓ | ✓ |
| IRF2 | ✓ | ✓ | ✓ | ✓ | ✓ |
| IRF7 | ✓ | ✓ | ✓ | ✓ | ✓ |
| ISG15 | NT | ✓ | ✓ | ||
| LAMP3 | NT | ✓ | |||
| LMO2 | NT | ✓ | |||
| MAP3K14 | NT | ✓ | ✓ | ✓ | |
| MDA5 | ✓ | ✓ | ✓ | ✓ | ✓ |
| MKX | NT | ✓ | |||
| MYD88 | ✓ | ✓ | ✓ | ✓ | |
| PCTK2 | NT | ✓ | |||
| PHF11 | ✓ | ||||
| PMAIP1 | NT | ✓ | |||
| PRIC285 | NT | ✓ | |||
| PSMB9 | ✓ | ✓ | ✓ | ||
| RIG-I | ✓ | ✓ | ✓ | ✓ | |
| SAMD4A | ✓ | ✓ | |||
| SMAD3 | ✓ | ||||
| SSBP3 | ✓ | ✓ | ✓ | ||
| UBE2L6 | NT | ✓ | |||
| UPP2 | ✓ | ||||
| VAMP5 | NT | ✓ | ✓ |
1
NT refers to a gene that was not tested in the particular screen.
2
A tick mark represents a gene that significantly synergized with ZAP (P<0.05).